Home » Publications » Canagliflozin reprograms the aging hippocampus in genetically diverse UM-HET3 mice and attenuates Alzheimer’s-like pathology

Canagliflozin reprograms the aging hippocampus in genetically diverse UM-HET3 mice and attenuates Alzheimer’s-like pathology

Jayarathne H, Manchanayake DH, Chimienti N, Kadri O, Gurdziel K, Kim S, Jang H, Ginsburg BC, Miller RA, Yakar S, Sadagurski M. Canagliflozin reprograms the aging hippocampus in genetically diverse UM-HET3 mice and attenuates Alzheimer’s-like pathology. bioRxiv [Preprint]. 2025 Jun 15:2025.06.10.658747. doi: 10.1101/2025.06.10.658747. PMID: 40661442; PMCID: PMC12259070.

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